CDF it all: Consensus prediction of intrinsically disordered proteins based on various cumulative distribution functions
نویسندگان
چکیده
منابع مشابه
study of hash functions based on chaotic maps
توابع درهم نقش بسیار مهم در سیستم های رمزنگاری و پروتکل های امنیتی دارند. در سیستم های رمزنگاری برای دستیابی به احراز درستی و اصالت داده دو روش مورد استفاده قرار می گیرند که عبارتند از توابع رمزنگاری کلیددار و توابع درهم ساز. توابع درهم ساز، توابعی هستند که هر متن با طول دلخواه را به دنباله ای با طول ثابت تبدیل می کنند. از جمله پرکاربردترین و معروف ترین توابع درهم می توان توابع درهم ساز md4, md...
Intrinsically disordered proteins.
Our understanding of protein function has been predominated by the view that proteins need to adopt a defined three dimensional structure to be able to carry out their function. Indeed, crystal structures of numerous proteins have been instrumental in establishing the structure– function paradigm. For example, the structures of numerous enzymes have highlighted the need for particular chemical ...
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In the same way that neither a messy lab bench nor a clean one is a reliable indicator of a researcher’s productivity, a protein’s function cannot be judged solely on the basis of its neatly folded and stable domains. As evidenced by recent work discussed in this Select, we are learning that intrinsically disordered regions feature in many of the cell’s most productive multitaskers, proteins wh...
متن کاملComputational approaches for inferring the functions of intrinsically disordered proteins
Intrinsically disordered proteins (IDPs) are ubiquitously involved in cellular processes and often implicated in human pathological conditions. The critical biological roles of these proteins, despite not adopting a well-defined fold, encouraged structural biologists to revisit their views on the protein structure-function paradigm. Unfortunately, investigating the characteristics and describin...
متن کاملCECAM workshop on Intrinsically Disordered Proteins
With the increasing need to integrate different areas of science in the study of intrinsically disordered proteins we arranged a meeting entitled “Intrinsically Disordered Proteins: Connecting Computation, Physics and Biology” in Zürich in September 2013. The aim of the meeting was to bring together scientists from a range of disciplines to provide a snapshot of the field, as well as to promote...
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ژورنال
عنوان ژورنال: FEBS Letters
سال: 2009
ISSN: 0014-5793
DOI: 10.1016/j.febslet.2009.03.070